KMID : 0438420140210030223
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Korean Journal of Bone Metabolism 2014 Volume.21 No. 3 p.223 ~ p.226
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Intravenous Zoledronate for a Patient with Paget¡¯s Disease
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Kim Ki-Choul
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Abstract
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Paget¡¯s disease (PD) of bone is characterized by increase of bone resorption by atypical osteoclasts, followed by rapid new bone formation resulting in a disorganized mosaic bone. Although the pathophysiology is not fully understood, bisphosphonate, which is a potent anti-resorptive agent for treatment of osteoporosis, have been the most effective agents available for the treatment of PD. We report a case of PD of bone in a 49-year-old woman patient, who was treated with intravenous zoledronate.
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KEYWORD
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Bone density conservation agents, Diphosphonates, Osteitis deformans
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